The Spartan-6 FPGA 9K Block RAM Initialization issue does affect the DPD IP as the core does use 9K BRAM. Block RAM used in the 9K mode (RAMB8BWER) can fail to initialize user specified data or default values (all zeros) during configuration inall Spartan-6devices. You should review the MAP report to see if your design is using the RAMB8BWER.
If your design does contain a RAMB8BWER, see the Spartan-6 Errata (including EN148) and (Xilinx Answer 39999) for more details on the Spartan-69k block RAM initialization issue. For a detailed list of Digital Pre-Distortion (DPD) Release Notes and Known Issues, see (Xilinx Answer 33521)