If you use a 32-bit versions of iMPACT, Analyzer, and Cse Server on a 64-bit OS, you will see the following messages in iMPACT -
"WARNING:iMPACT:923 - Cannot find cable, check cable setup" / "Cable connection failed"
and in ChipScope Pro -
"INFO: Source driver files not found.
INFO: The Platform Cable USB is not detected. Please connect a cable. If a cable is connected, please disconnect and reconnect to the USB port, follow the instructions in the 'Found New Hardware Wizard', then retry the Cable Setup operation.
INFO: Cable connection failed.
ERROR: Failed to open Xilinx Platform USB Cable. See message(s) above."
The cable will not connect.